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Endocrine Abstracts

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ea0070aep254 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Chronic activation of adaptive immunity in type 2 diabetes

Garstka Malgorzata , Liu Shan , Ren Xu , Kong Ying , Xu Xiaoqiang , Li Xiaozhen , Jiao Yang , Huang Na , Min Xiaoyun , Ma Ning , Li Baohua , Li Ke , Xu Jing

Context: Type 2 diabetes (T2D) is associated with an increased incidence of infections and several cancers. Although low-grade inflammation and certain immune defects have been found in diabetic patients, the role of adaptive immune response remains to be fully elucidated.Objective: We aimed to explore whether patients with T2D show defects in the activation of T cells.Design: Immune cell phenotypes, T cell functional reactivity, s...
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ea0081ep7 | Adrenal and Cardiovascular Endocrinology | ECE2022

A phase III trial of recombinant human growth hormone in pediatric patients with growth failure caused by chronic kidney disease

Xu Hong , Tang Xiaoshan , Shen Qian , Chen Jing , Fang Xiaoyan , Zhang Aihua , Zhao Fei , Chen Qiuxia , Huang Wenyan , Wang Ping , Sun Liwen , Xiao Huijie , Xu Ke , Liu Xiaorong , Chen Zhi , Chen Chaoying , Tu Juan , Wu Yubing , Wang Xiuli , Mao Jianhua , Lu Zhihong , Wang Jingjing , Nie Xiaojing , Yu Zihua , Huang Jun , Liu Cuihua , Cao Guanghai , Li Yufeng , Zhu Yaju , Zhang Jianjiang , Wang Miao , Wang Mo , Yang Haiping

Background and objective: Children with chronic kidney disease (CKD) have impaired growth that leads to short stature in adulthood and treatment with recombinant human growth hormone (rhGH) is associated with improved growth. This study aimed to evaluate the efficacy and safety of daily rhGH (Jintropin®) in children in China with growth failure caused by CKD prior to transplantation.Methods: Prepubertal patients (2–13 years old) with CKD-relate...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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